Trends in death attributed to myocardial infarction, heart failure and pulmonary embolism in Europe and Canada over the last decade

Trends in death attributed to myocardial infarction, heart failure and pulmonary embolism in Europe and Canada over the last decade

Laribi S1, Aouba A2, Resche-Rigon M3, Johansen H2, Eb M2, Peacock FW2, Masip J2, Ezekowitz JA2, Cohen-Solal A1, Jougla E2, Plaisance P1, Mebazaa A1QJM. 2014 Oct;107(10):813-20.

Source :

  • 1From the INSERM, UMRS 942, Biomarkers and cardiac diseases, 75010 Paris, France, Emergency Department, APHP, Hôpital Lariboisière, 75010 Paris, France, GREAT network (http://www.greatnetwork.org), Center of Epidemiology for Medical Causes of Death (Inserm, CépiDc, Kremlin-Bicêtre), France, Univ Paris Diderot, Sorbonne Paris Cité, 75010 Paris, France, Department of Biostatistics and Clinical Epidemiology, APHP, Saint-Louis University Hospital, INSERM U717, Paris, France, Department of Epidemiology and Community Medicine, University of Ottawa, Canada, Baylor College of Medicine, Houston, TX, USA, Intensive Care Department, Consorci Sanitari Integral, University of Barcelona, Spain, Mazankowski AlbertaHeart Institute, Edmonton, Alberta, Canada, Department of Cardiology, AP-HP, Hôpital Lariboisière, 75010 Paris, France and Department of Anesthesiology and Critical Care, APHP, Hôpital Lariboisière, 75010 Paris, France From the INSERM, UMRS 942, Biomarkers and cardiac diseases, 75010 Paris, France, Emergency Department, APHP, Hôpital Lariboisière, 75010 Paris, France, GREAT network (http://www.greatnetwork.org), Center of Epidemiology for Medical Causes of Death (Inserm, CépiDc, Kremlin-Bicêtre), France, Univ Paris Diderot, Sorbonne Paris Cité, 75010 Paris, France, Department of Biostatistics and Clinical Epidemiology, APHP, Saint-Louis University Hospital, INSERM U717, Paris, France, Department of Epidemiology and Community Medicine, University of Ottawa, Canada, Baylor College of Medicine, Houston, TX, USA, Intensive Care Department, Consorci Sanitari Integral, University of Barcelona, Spain, Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada, Department of Cardiology, AP-HP, Hôpital Lariboisière, 75010 Paris, France and Department of Anesthesiology and Critical Care, APHP, Hôpital Lariboisière, 75010 Paris, France From the INSERM, UMRS 942, Biomarkers and cardiac diseases, 75010 Paris, France, Emergency Department, APHP, Hôpital Laribois
  • 2From the INSERM, UMRS 942, Biomarkers and cardiac diseases, 75010 Paris, France, Emergency Department, APHP, Hôpital Lariboisière, 75010 Paris, France, GREAT network (http://www.greatnetwork.org), Center of Epidemiology for Medical Causes of Death (Inserm, CépiDc, Kremlin-Bicêtre), France, Univ Paris Diderot, Sorbonne Paris Cité, 75010 Paris, France, Department of Biostatistics and Clinical Epidemiology, APHP, Saint-Louis University Hospital, INSERM U717, Paris, France, Department of Epidemiology and Community Medicine, University of Ottawa, Canada, Baylor College of Medicine, Houston, TX, USA, Intensive Care Department, Consorci Sanitari Integral, University of Barcelona, Spain, Mazankowski AlbertaHeart Institute, Edmonton, Alberta, Canada, Department of Cardiology, AP-HP, Hôpital Lariboisière, 75010 Paris, France and Department of Anesthesiology and Critical Care, APHP, Hôpital Lariboisière, 75010 Paris, France.
  • 3From the INSERM, UMRS 942, Biomarkers and cardiac diseases, 75010 Paris, France, Emergency Department, APHP, Hôpital Lariboisière, 75010 Paris, France, GREAT network (http://www.greatnetwork.org), Center of Epidemiology for Medical Causes of Death (Inserm, CépiDc, Kremlin-Bicêtre), France, Univ Paris Diderot, Sorbonne Paris Cité, 75010 Paris, France, Department of Biostatistics and Clinical Epidemiology, APHP, Saint-Louis University Hospital, INSERM U717, Paris, France, Department of Epidemiology and Community Medicine, University of Ottawa, Canada, Baylor College of Medicine, Houston, TX, USA, Intensive Care Department, Consorci Sanitari Integral, University of Barcelona, Spain, Mazankowski AlbertaHeart Institute, Edmonton, Alberta, Canada, Department of Cardiology, AP-HP, Hôpital Lariboisière, 75010 Paris, France and Department of Anesthesiology and Critical Care, APHP, Hôpital Lariboisière, 75010 Paris, France From the INSERM, UMRS 942, Biomarkers and cardiac diseases, 75010 Paris, France, Emergency Department, APHP, Hôpital Lariboisière, 75010 Paris, France, GREAT network (http://www.greatnetwork.org), Center of Epidemiology for Medical Causes of Death (Inserm, CépiDc, Kremlin-Bicêtre), France, Univ Paris Diderot, Sorbonne Paris Cité, 75010 Paris, France, Department of Biostatistics and Clinical Epidemiology, APHP, Saint-Louis University Hospital, INSERM U717, Paris, France, Department of Epidemiology and Community Medicine, University of Ottawa, Canada, Baylor College of Medicine, Houston, TX, USA, Intensive Care Department, Consorci Sanitari Integral, University of Barcelona, Spain, Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada, Department of Cardiology, AP-HP, Hôpital Lariboisière, 75010 Paris, France and Department of Anesthesiology and Critical Care, APHP, Hôpital Lariboisière, 75010 Paris, France.

Abstract : BACKGROUND : Worldwide, cardiovascular diseases and cancer account for ?40% of deaths. Certain reports have shown a progressive decrease in mortality. Our main objective was to assess mortality trends related to myocardial infarction (MI), heart failure (HF) and pulmonary embolism (PE). METHODS : MI, HF and PE were studied as cause of death based on the analysis of death certificates in Canada (C), England and Wales (E), France (F) and Sweden (S). We also used a multiple cause approach. Age-standardized death rates (SDR) were calculated. RESULTS : The SDR for MI, HF or PE as the underlying cause of death, all decreased during the last decade. The decrease in SDR secondary to MI exceeded that for HF or PE. Concerning multiple cause of death, a greater decrease was also found for MI, compared with HF or PE. CONCLUSIONS : We confirm the beneficial trends in SDR with MI, HF or PE both as underlying or multiple causes in the studied countries. For HF and PE, multiple cause approach seems more accurate to describe the burden of these two pathologies. Our study also suggests that more efforts should be dedicated to HF and PE in order to achieve similar trends than in MI.